virus
Virus
LOTTERY,
attendance
envelope.
Flu has
envelope,
cold no.
HPV life cycle (for project)
Poliovirus Vaccine Trial Shows Promise for Brain Tumor
Better batteries through viruses
HIV
Capsid also injected, but digested.
HIV life cycle: reverse transcriptase, integrase, protease (44 MB) (HHMI)
HIV life cycle: reverse transcriptase, integrase, protease (44 MB)
HIV
diversity
HIV treatment: AZT blocks reverse transcriptase (HHMI)
HIV treatment: Ritonavir protease inhibitor (HHMI)
Retroviruses and retroviral-like transposons: jumping viruses
Endogenous retroviruses: life cycle and ancestral implications
Repetitive DNA: LINEs, SINEs, and ALUs (transposons); whales and hippos, oh my
flu
Respiratory system, nasal; 8 negative sense strands -> positive mRNA;
RNA dependent
RNA polymerase
Subtypes = alleles, but no parents; surface proteins=antigens.
Hemagglutinin (H) 17 subtypes (3 human): entry, Neuraminidase (N) 9 subtypes: exit.
Vaccines are H1N1, H3N2, + B strain = trivalent; nasal spray was attenuatedrather than inactivated.
Therapeutic antibodies neutralize the flu virus: an alternative to vaccines?
bird-flu
Flu A can be bird/swine (also B, C) Hong Kong 1968. Vaccine 2 A + 1 B each year.
Pigs
can get flu from birds & humans, recombine -> human H1N1
Genetic recombination in flu virus (Note: no crossing over) (HHMI)
Dengue Virus structure: like other flaviviruses such as Zika and West Nile
Dengue virus enters cell by endocytosis (HHMI)
Dengue has lipid envelope,
CAPSID and
RNA genome;
ZIKA skin cells?
Dengue virus lecture by Eva Harris, 2010 6:30-8:00 enters cell by endocytosis
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Banana, orange... honey locust, K. coffee are fruits.
Fruits have seeds, inside are embryos. So is peanut: eat embryo + food/nutrients for embryo.
Seeds on Cavendish banana inferior ovary? Ripe dots; eat ovary.
Reproduce cloning; underground stem suckers.
Easy clone plants - genetically identical; do not go thru embryo: apple graft.
Animals harder, especially mammals - embryo stage - except hydra.
Egg: 2ndary oocyte. Diploid cell is unnatural: not really zygote/Fallopian - how to fool?
So zygote undergoes mitosis -> early embryo undifferentiated (same DNA) expression.
Inner cell mass/placenta with uterine wall: "cleavage".
Stem cells therapy - spinal cord damage.