mendel
Scientific: observe, control variables, statistics/size. Bring
SUNFLOWER pollen/carpel/seeds.
St Thomas's Abbey in Brno Augustinian monastery Czech Republic
genes
Dominates conversation, recedes silent; but some people interm/incomplete: aggressive/passive.
Many genetic diseases RECESSIVE: sickle. Lactase Non-Persistence unexpressed after weaning incomplete?
Epigenetic inheritance (you are what your grandmother ate) 3:00-7:10 agouti mice and epigenome (NOVA)
mendelian
REMOVE self-fertilize!
Parents mustb HOMOZYG then preview
meiosis:
separation explains
HETEROZYG F1.
True-breeding=pure-bred: black hair in Asia!
segregation
Exercise:
1/2
Many diseases are
RECESSIVE (lactose, sickle): can predict; but
PUNNETT easier random!
Independent assortment: a Mendelian view of 2 genes
Mendelian Inheritance: Punnett Squares, testcross, X link
recessive
bring
WHITE & colored paper: albino reflects nothing (next topic on giraffe)
But oversimplified: black hair can turn
WHITE - no pigment!
phenotype
Who is a
WHITE person? Albino.
punnett
Similar to pea: pigment
BROWN;
based on
MEIOSIS gametes:
Mendel knew not genes/meiosis -> inheritance from
ANCESTOR evolution.
Note
CAP M for dominant
LOWER m recessive.
Use
PAINT example:
XX x
XY ->boy/girl.
Exercise:
1/2
punnett_square
Exercise:
answer
testcross
MARKERS
Genetic linkage: dihybrid crosses and gene mapping
incomplete_dominance
Also chlorophylls, hair.
Blonde hair baby -> darker due to hormones; my hair has turned white.
Familial Hypercholesterolaemia:
FH heterozygote has few liver
LDL receptors, cardiovascular disease.
bloodABO
Exercise:
drag the X to
boxes.
Donated blood only RBC, no plasma.
Blood types and blood compatibility
blood_donation
Type A has anti-B; Type O has both.
XLinked
SelfQ=100%
EmmaRobertson: father & son color-blind; next son color-blind=50% (mother mustb carrier)
male baldness higher androgen receptor activity on X: castrated produce no androgens; + chromosome 20
SHORT chap, start chap 8.
===
7e Anim#3 Krebs: 1=d 2=A?
#6 PPump: 1=E to outside! 2=c 3=e d=T e=F not permeable!
post: 1=F! (CELLULAR respiration) 2=T 3=b 4=d 5=F 6=d 7=T 8=F 9=A 10=T
11=F 12=d 13=F 14=T 15=T 16=d 17=e 18=B matrix 19=c 20=c inner membrane